AB1231 PROFILE OF OSTEOPOROSIS IN YOUNG WOMEN: EXPERIENCE FROM A POPULATION IN SOUTHERN MOROCCO

Background Osteoporosis is a generalized skeletal disease characterized by low bone density and alterations in microarchitecture. Current definitions recommendations focus more on postmenopausal osteoporosis with number of studies young pré-menopausal women, which makes it difficult to estimate the prevalence this population. Objectives To establish determine etiologies women their management according experience our department. Methods Retrospective descriptive analytical study including 97 female patients aged less than 45 years, who performed densitometry measurement between years 2014 2022. Data were collected from database. was retained if T score or equal -2.5. Women older followed for genetic osteopathy excluded study. Results There The average age 25 years. Early menopause found 15% cases (10% after chemotherapy). secondary endocrinopathy 17% (5% diabetes, 10% primary hyperparathyroidism, 2% Cushing’s syndrome). It systemic chronic inflammatory rheumatism 45% (29% rheumatoid arthritis, 12% spondyloarthropathy, 3% lupus erythematosus 1 % Horton’s disease). other pathologies renal failure cases, notion prolonged use corticosteroids 21% hormone therapy breast neoplasia 14%. had at least one osteoporotic vertebral fracture. mean mineral (BMD) both femurs 0.727g/cm2. BMD spine 0.965g/cm2. 11% these treated oral anti-osteoporotic drugs, 35% supplemented vitamin D calcium. Conclusion discovery rare hence scarcity category women. may be metabolic drug-induced origin related diseases. should investigated presence risk factors order limit fractures. Reference [1] Pepe J, Body Hadji P, McCloskey E, Meier C, Obermayer-Pietsch B, et al. Premenopausal Women: A Clinical Narrative Review ECTS IOF. Journal Endocrinology & Metabolism. 2020 Aug 1;105(8):2487-506. Acknowledgements: NIL. Disclosure Interests None Declared.